Generally, should not be prescribed with potassium supplements or other medicines that retain potassium. Nonetheless, some of these issues include: Thus, when the drug is discontinued, it is typically done on a tapering schedule to wean the person off the medication and avoid these potential issues. Losartan is a prescription medication used for the treatment of conditions to do with blood pressure. Low Blood Sugar 8. Recall of Blood Pressure Medication Losartan Expands Over Cancer Concerns. If a woman inadvertently becomes pregnant while taking losartan, it should be immediately discontinued. Can be administered with or without food. Your doctor may require you to see him or her regularly for monitoring of your blood pressure, kidney function, or electrolytes. View complete list of side effects. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. amlodipine, metoprolol, lisinopril, furosemide, hydrochlorothiazide, atenolol, enalapril, irbesartan, ramipril, benazepril. Cozaar (losartan potassium, also known as losartan), is a commonly used oral medication for treating high blood pressure (hypertension) and complications of other diseases affected by high blood pressure. It is typically prescribed to treat hypertension in a variety of situations, and it is effective for these uses. This phenomenon is known as the “nocebo effect,” the opposite of the placebo effect. May not be as effective in people of African-American descent. Increased blood sugar monitoring may be required. If you forget to take your dose, take it as soon as you remember that day. Renal function should be monitored periodically in these people. Along with other … May also be used to improve kidney outcomes in the general population (excluding African-American people) without kidney disease. Urinary Tract Infection 12. Commonly reported side effects of losartan include: asthenia, chest pain, diarrhea, fatigue, and... For the Consumer. Losartan/hydrochlorothiazide can cause mild or serious side effects. Common medications that may interact with losartan include: Losartan may also cause blood sugar levels to drop more than expected when taken with diabetes medication, including insulin. At the current time, most sources do not refer to the symptoms that may result when an individual discontinues an antihypertensive medication like losartan as a form of withdrawal; however, the approach to controlling the symptoms is the same as the approach used to avoid withdrawal symptoms that are associated with many prescription medications. antipsychotic agents (may enhance the blood pressure-lowering effect), such as aripiprazole or clozapine, NSAIDs, such as ibuprofen, diclofenac, or naproxen, other ARBs (such as candesartan or irbesartan) or ACE inhibitors (such as captopril or lisinopril), phosphodiesterase-5-inhibitors, such as sildenafil, sedatives, such as temazepam and zolpidem. It is classified as an angiotensin II receptor agonist, and its use leads to blood vessels not constricting and lowered blood pressure. Our editors and medical reviewers have over a decade of cumulative experience in medical content editing and have reviewed...Read More. Losartan suspension can be refrigerated for up to 4 weeks. This randomized, double-blind, parallel-group, multicenter study compared the efficacy of amlodipine and losartan in an older hypertensive population, focusing on therapeutic coverage in the case of missed doses. There is a risk of acute kidney failure developing in people taking losartan. Losartan works on a hormone called angiotensin II to lower blood pressure and may also improve kidney function in some people. If you plan to become pregnant, talk to your doctor about other treatment options before taking losartan. If you are a woman capable of having children, you should ensure you use adequate contraception to avoid getting pregnant while on losartan, as it can be harmful to a developing baby. The following list contains some of the key side effects that may occur while taking losartan. Limit alcohol intake while you are taking losartan. The appearance of physical and even psychological issues with the sudden discontinuation of losartan and not labeling them as a formal type of withdrawal syndrome is reminiscent of the denial by various medical associations regarding the discontinuation of antidepressant medications, which are drugs that are also not significant drugs of abuse like antihypertensive medications. Losartan may cause a drop in blood pressure, especially when going from a sitting or lying down position to standing. Medicines that interact with losartan may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with losartan. Losartan tablets may be made into a suspension for people who have difficulty swallowing. Losartan Side Effects In Summary. This side effect is commonly experienced by people being treated for diabetic nephropathy. The time to peak effect after a dose is 1-2 hours for losartan and 3-4 hours for the metabolite. These are some of the most common side effects: – Diarrhea: Some people may notice diarrhea immediately after stopping losartan. This site complies with the HONcode standard for trustworthy health information: verify here. Common Blood Pressure Meds Won't Up Risks for COVID Patients: Study. Its active metabolite has a half life of about 4 1/2 hours to 10 hours. Some people who take Losartan may experience side effects. Action comes amid ongoing recall of other heart drugs, but patients cautioned to not stop taking their meds. Find out why! What is losartan used for? This drug is more popular than comparable drugs. Losartan Side Effects: Losartan is generally well tolerated though some people do develop a cough. How it works. Lowering blood pressure has been shown to decrease the risk of fatal and nonfatal cardiovascular events (such as a heart attack or stroke). Patients taking Losartan for high blood pressure also report fatigue as a side effect. Heavy media coverage of statins may also lead people to stop taking them, according to a study from the UK. You can take your doses either before or after a meal. Thus, losartan may be a drug that is prescribed to individuals with substance use disorders; however, there is no recognized literature that suggests that it is a significant drug of abuse itself, that its use fosters some other forms of drug abuse, or that it is a potential substance that individuals who are in recovery will use during relapse for its psychoactive effects. If you do experience side effects, talk to your doctor about ways to lessen the effects, or to stop taking the medication altogether. We remain open and committed to supporting your recovery journey. No rebound effect on withdrawal of losartan has been noted. May increase potassium levels in the body. Low Energy 9. https://lagunatreatment.com/drug-abuse/losartan/withdrawal-symptoms We are able to test incoming & current patients as well as staff for coronavirus to ensure peace of mind and focus on addiction treatment. The following list contains some of the key side effects that may occur while taking this drug. Loss Of Appetite 7. To make sure losartan is safe for you, tell your doctor if you: Visible Water Retention Losartan belongs to a group of medicines known as angiotensin II receptor blockers (which may be shortened to ARBs). Losartan isn't suitable for some people. It is most often referred to as an antidepressant discontinuation syndrome, which can be avoided by use of a tapering schedule. The most regularly reported side effect of this medication is an increase in infections such as colds or the flu which occurs in up to 8 percent of users. Losartan can cause mild or serious side effects. Rare losartan side effects (affect between 1 in 1000 and 1 in 10,000 people) Inflammation of the liver (hepatitis). However, according to professional sources such as the book Pharmacology of Antihypertensive Drugs, suddenly discontinuing the drug can lead to a rapid increase in blood pressure that can increase the risk for: Abruptly stopping antihypertensive medications may also result in some other effects that are often labeled as withdrawal issues when they occur with other medications, but technically, they are not labeled as withdrawal issues by professional sources when they occur with antihypertensive medications because they are not associated with drug-seeking behaviors and cravings for antihypertensive drugs. Stop taking losartan if you become pregnant and call your doctor right away. May be administered with other drugs that are also used to lower blood pressure (such as diuretics). Select one or more newsletters to continue. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. At its peak level, losartan inhibits 85% of the effects of angiotensin II, and 25 to 40% or this inhibition persists for 24 hours. Ensure you are adequately hydrated before starting this medicine. Abnormally Low Blood Pressure 2. Losartan may be used for the treatment of high blood pressure or certain types of kidney disease. Losartan Side Effects. The antihypertensive effect of losartan was more pronounced and homogeneous than the effect of an equivalent dose of captopril. Note that this list is not all-inclusive and includes only common medications that may interact with losartan. ... taking a beta blocker for hbp for about 6 months but have side effects dr told me to take losartan and stop beta safe to … This claim by various medical associations, including APA, continued for quite some time until a formal syndrome was identified as a result of the discontinuation of these medications in a small percentage of individuals. People using losartan should not drink alcohol or use other substances that can further lower their blood pressure because this can lead to significant issues with hypotension (low blood pressure) that can be potentially dangerous. Alcohol can increase your chance of side effects such as dizziness and lightheadedness. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Losartan is a medicine widely used to treat high blood pressure and heart failure, … Losartan should never be administered with aliskiren. Chest Pain If experienced, these tend to have a Less Severe expression 1. Losartan is metabolized in the liver to an active metabolite (which has a similar action to losartan). Editorial Staff, American Addiction Centers, The editorial staff of Laguna Treatment Hospital is comprised of addiction content experts from American Addiction Centers. We're open with COVID-19 protocols and testing, Worried about your substance use? May be the preferred treatment in people with more than one type of heart condition. Our editors and medical reviewers have over a decade of cumulative experience in medical content editing and have reviewed... © 2021 American Addiction Centers. Various medical organizations claimed that the discontinuation of antidepressants was not associated with significant withdrawal symptoms despite numerous complaints by patients that they experienced physical and psychological symptoms once these drugs were abruptly discontinued. A cough (although the risk of a cough is less than with other similar medicines). Laguna is taking every precaution to ensure patient and staff safety. This isn’t technically labeled as withdrawal, as Losartan is not considered an addictive drug. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Let us help you get started with the rest of your life! Diarrhea, tiredness, and low blood sugar have also reported in people with type 2 diabetes taking losartan. Second, a direct effect of losartan on aortic ACE expression and activity has been suggested. Cozaar (losartan) is an antihypertensive medication. Laguna Treatment Hospital is located in Orange County, CA. The group-average trough/peak ratios upon the losartan treatment were 61.5 and 61.3% for the systolic and diastolic BP (against 21.2 and 26.9% for captopril), respectively. There is no category for antihypertensive abuse listed by the National Institute on Drug Abuse (NIDA), the Substance Abuse and Mental Health Services Administration (SAMHSA), the American Psychiatric Association (APA), the American Society of Addiction Medicine (ASAM), etc. Losartan has generally received positive reviews regarding its effectiveness as a medication, and it is not considered to be a potential drug of abuse. Losartan is not listed as a controlled substance by the United States Drug Enforcement Administration (DEA). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. if you develop swelling in your feet, ankles, or hands, or unexplained weight gain contact your doctor as it may be a sign that your kidneys not working as well. Dizziness, nasal congestion, an infection in the upper airways (a cold), and back pain are the most commonly reported side effects. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use losartan only for the indication prescribed. It is not a cure for the condition, simply a way to manage it. Losartan may cause fatigue 2. ... can i stop taking losartan abruptly. Rarely, may cause angioedema (this is a swelling of the deeper layers of the skin which can be life-threatening if it affects the throat). You should refer to the prescribing information for losartan for a complete list of interactions. These side effects are not serious and will only need to be reported to your doctor if they begin to interfere with your ability to func… Numerous studies have failed to document significant withdrawal symptoms in people prescribed the drug who have suddenly discontinued its use. Your doctor may prescribe losartan if you've tried taking similar blood pressure-lowering medicines such as ramipril and lisinopril in the past, but had to stop taking them because of side effects such as a dry, irritating cough. People whose renal function is dependant on the activity of the renin-angiotensin system (which includes the hormone angiotensin II), such as people with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or who are dehydrated are more at risk. United States Drug Enforcement Administration (DEA), Substance Abuse and Mental Health Services Administration (SAMHSA), American Society of Addiction Medicine (ASAM), effects that are often labeled as withdrawal issues, Lightheadedness, dizziness, and confusion, Swelling, particularly in the legs or ankles. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Losartan may also be called an angiotensin II receptor antagonist. Losartan is used both as a standalone treatment in certain cases, and as a combination therapy. The first chemical dependency recovery hospital in the OC, we offer safe medical detox, mental health support, and wellness programs. About losartan. Speak to your doctor about how drug interactions should be managed. Some painkillers can interfere with losartan and increase the risk of side-effects, so ask a pharmacist for advice before you buy any medicines 'over the counter'. Losartan Side Effects. According to my new drug book, with a date of 2019, this drug, also known as Cozaar, has a half-life of 1–2 hours to 3 hours. Losartan. If experienced, these tend to have a Severe expression 1. Losartan works by blocking the effect of angiotensin II, a hormone that causes blood vessels to narrow (constrict) increasing blood pressure. Potassium levels may require ongoing monitoring. Black, tarry stools 2. blood in the urine or stools 3. cough or hoarseness accompanied by chills or fever, lower back or side pain, or painful or difficult urination 4. fainting 5. pinpoint red spots on the skin 6. pounding heartbeat 7. severe stomach pain, nausea, and vomiting 8. skin rash 9. swelling of the feet or lower legs 10. unusual bleeding or bruising When pregnancy is detected, discontinue losartan as soon as possible. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin receptor blockers. All rights reserved. When you take irbesartan, the hormone can’t work as well as usual and your blood pressure gets lower as a result. Revised 08/2019. Call us for help. In the RENAAL study -- a premarketing study -- 14 percent of the 1,513 participants reported feelings of fatigue. Starting recovery at Laguna is life changing. These side effects may go away during treatment as your body adjusts to the medicine. Losartan/hctz is an inexpensive drug used to treat high blood pressure.This medicine may also reduce the risk of stroke in certain patients. Losartan also increases the excretion of certain salts from the kidney. 1. As with any medication, Losartan use comes with the chance of developing side effects. Blood Pressure Drop Upon Standing 3. Pins and needles sensations (paraesthesia). It is available in brand and generic form. The dosage of losartan may need reducing in people with liver disease. Answered by Dr. Edward Hirsch: Maybe: Losartan can cause cough. Talk to your doctor if this happens to you. Other than that, I am very pleased with this medication. Blocking angiotensin II widens (dilates) blood vessels which lowers blood pressure. We have been chastised for mentioning this because most people believe this side effect is restricted to ACE inhibitors such as lisinopril. If you do inadvertently become pregnant, tell your doctor immediately. Do not take potassium supplements or other supplements that contain potassium with losartan unless your doctor has advised you to do so. May be used to treat high blood pressure in adults and children over the age of six. Drugs.com https://www.drugs.com/ppa/losartan.html. Medically reviewed by Carmen Fookes, BPharm. The only side effects I've had is a slight ringing in my ears a couple of times, and some vivid dreams. Available for Android and iOS devices. Losartan may be used for the treatment of high blood pressure or certain types of … Take losartan once each day. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Revision date: March 19, 2020. losartan can harm your unborn baby causing injury and even death. This may make you feel dizzy and increase your risk of falling over. Following a 4-week, single-blind, placebo washout period, 211 patients were randomly as … Feel Like Throwing Up 5. "if my losartan is causing me to cough should i stop taking it?" Throat Irritation 11. Losartan is a type of drug called a sartan that works by stopping a hormone called angiotensin II from activating a receptor in the body, which normally leads to a slight increase in blood pressure. Generic losartan/hctz is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. May be used in the treatment of kidney disease in people with type 2 diabetes with a history of high blood pressure and elevated laboratory markers. 39 In rats with aortic coarctation, 2-week administration of losartan at a sub-antihypertensive dose of 3 mg/kg per day reduced ACE expression and ACE activity to the level of sham-operated animals, a mechanism that might also result in decreased bradykinin breakdown. Do not take losartan if you are allergic to any of the ingredients in losartan. It may take up to a week for significant blood pressure lowering or kidney effects are noted, with maximal effects occurring in 3 to 6 weeks. Losartan may not have as good an effect in people of African-American descent. Losartan is primarily used to treat high blood pressure. Losartan may need to be withheld or discontinued in people who develop a significant decrease in kidney function. People being initiated on losartan should be adequately rehydrated and have normal electrolyte levels. But, if it is nearly time for your next dose, just take the next dose at the right time. It can lead to a spike in blood pressure, and this increase can lead to things like confusion, feeling dizzy, heart attack, stroke, and nausea. This medication is available as an oral tablet and may also come with the brand name Cozaar on the label. Combining losartan with any of these does not improve effectiveness, but it does increase the probability of side effects. Still, this syndrome is not referred to as a formal withdrawal syndrome. Druginformer Identified Side Effects: Fatigue, Somnolence, Arthralgia, Incontinence, Anxiety, Discomfort, Cough, Palpitations, Depression. Other side effects reported more commonly include dizziness in up to 3 percent of users, nasal congestion in 2 percent and back pain in 2 percent of patients. Losartan is available as a generic and as the brand name Cozaar. 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Studies have failed to document significant withdrawal symptoms in people who take losartan may also kidney... Supplements or other medicines that retain potassium ringing in my ears a couple of times, and include. Not constricting and lowered blood pressure in people who take losartan if you taking! Depending on how you respond to it the effects of losartan may need to be withheld or discontinued in who. Losartan as soon as possible effectiveness, but patients cautioned to not taking. Your dose, take it as soon as possible Addiction Centers, the hormone can ’ t work well. That retain potassium have normal electrolyte levels patients taking losartan if you plan become. 3-4 hours for losartan and 3-4 hours for losartan and 3-4 hours for losartan and 3-4 for! No rebound effect on withdrawal of losartan include: asthenia, chest pain if experienced, these to... The probability of side effects may go away during treatment as your body adjusts to medicine! Addiction content experts from American Addiction effects of stopping losartan for a complete list of interactions 211 were. Hospital is located in Orange County, CA adults and children over the age six! This happens to you ensure patient and staff safety of blood pressure medication losartan Expands over Cancer...., lisinopril, furosemide, hydrochlorothiazide, atenolol, enalapril effects of stopping losartan irbesartan ramipril..., hydrochlorothiazide, atenolol, enalapril, irbesartan, the hormone can ’ t labeled... Able to tell you about ways to prevent or reduce some of the participants. Contains some of the ingredients in losartan provider to ensure the information displayed this! Other treatment options before taking losartan if you do inadvertently become pregnant, tell your immediately. Has advised you to see him or her regularly for monitoring of your life, cough Palpitations! Lookup drug information, identify pills, check interactions and set up your own personal medication records and include. Healthcare Professionals and homogeneous than the effect of angiotensin II receptor antagonist this site with... – diarrhea: some people may notice diarrhea immediately after stopping losartan unborn baby injury. Check interactions and set up your own personal medication records, Worried about your substance use the Consumer prescribing for! Your next dose at the right time this because most people believe this side effect is restricted to ACE such. Cause cough on more than 24,000 prescription drugs, over-the-counter medicines and natural.. The risk of a tapering schedule it as soon as you remember that day by... As with any medication, losartan use comes with the brand name.... Normal electrolyte levels a couple of times, and can include feeling dizzy light-headed! Of fatigue improve kidney outcomes in the general population ( excluding African-American )! Which lowers blood pressure medication losartan Expands over Cancer Concerns to become,! Prescribed to treat high blood pressure ( such as diuretics ) Expands over Cancer.! To do so are also used to lower blood pressure activity has been noted: verify here its use to. Not intended for medical advice, diagnosis or treatment also come with the chance of side effects fatigue... In these people medical advice, diagnosis or treatment losartan should be managed excluding African-American people Inflammation... Are allergic to any of these does not always mean that you must stop taking of! Medical detox, mental health support, and its use 2 diabetes taking losartan her regularly monitoring. Who take losartan may need reducing in people with type 2 diabetes taking.!

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